Vicki Stone Ph.D.
Research Interests: Dr Stone is responsible for directing research into the toxicological mechanisms by which air pollutant particle and gases as well as environmental particles cause adverse health effects, primarily in humans. Projects include regimes for testing the potential toxicity of particles that enter the body using both in vivo and in vitro models. Nanoparticle and environmental particulate air pollution projects (PM10) have concentrated on the mechanism of toxicity, and the properties of the particles that are responsible for making them toxic. This research includes toxicologists (Dr. David Brown), immunologists (Dr. Keith Guy and Dr. Lorna Proudfoot), cancer cell biologicsts (Dr. Janis MacCallum) and sport scientists (Dr Geraint Florida-James) in the Biomedicine Research Group at Napier University. The Biomedicine Research Group, via Dr. Stone forms part of the Edinburgh Lung and the Environment Group Initiative (ELEGI) http://www.ciredinburgh.co.uk/haslett/donaldson/donaldson.htm ), a collaboration with the University of Edinburgh and the Institute of Occupational Medicine. Current research projects: 1. Cellular and molecular responses to oxidative stress induced by inhaled toxins. This project is part of an ongoing project, now in its 7th year that investigates the focuses on the toxic mechanisms of ultrafine or nanoparticles. Funded by the Colt Foundation (http://www.coltfoundation.org.uk/). Collaboration with ELEGI. 2. The influence of particle size and composition on in vitro and in vivo biological models. Funded by DEFRA (http://www.defra.gov.uk/). Collaboration with ELEGI. 3. The effect of a short-term closure of a steel plant on the chemical composition and biological activity of Redcar and Cleveland PM10. Funded by DEFRA. Collaboration with ELEGI. 4. The effect of particles on macrophage migration and phagocytic function. Funded by Napier University. 5. The relationship between quartz particle surface contamination and potency in the lung. 6. The effect of ozone inhalation on the performance of elite athletes. Funded by British Olympic Medical Centre. 7. The relationship between Diabetic neuropathy and PM10 exposure. BooksJournal of Nanotoxicology |
By this Researcher
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