Paul C.H. Li Ph.D.

Li, Paul C.H.
Position Department / Business Unit
Associate Professor Chemistry
Institution Disciplines
Simon Fraser University Chemistry Physics
City State / Provence
Burnaby British Columbia
Country Website
Canada link
Fax

Paul C.H. Li, Ph.D is Associate Professor at Simon Fraser University, (British Columbia) Dr. Li's group are interested in carrying out various chemical and biochemical analysis which are enhanced by the use of microfluidic devices.

Dr Li's group is particularly focused on:
* Separation and analysis of bioactive compounds derived from natural sources, e.g. licorice.
* Analysis of various compounds based on contraction of cardiac muscle cells detected by an acoustic wave sensor.
* Analysis of various compounds based on their effect on the NFkB signalling pathway in Jurkat T cells using an EGFP reporter.

Their research goals are:

* To enhance various chemical and biochemical analysis by miniaturization so that analysis can be achieved in shorter time and with less reagents,
* To integrate these processes on-chip based on various microchip layout designs and various detection methodologies, and
* To develop cell-based analysis on-chip for testing of various compounds for drug screening and discovery.

Education

B.Sc., Chemistry and Physics, University of Hong Kong; M.Sc., Ph.D., Analytical Chemistry, University of Toronto

Career Highlights

Dr. Li's Courses at SFU include.

Chem 215: Introduction to Analytical Chemistry

Chem 316: Introductory Instrumental Analysis

Chem 819: Special Topics in Analytical Chemistry: Microfluidic lab-on-a-chip

Important Articles

  • Separation of fluorescent derivatives of hydroxyl-containing small molecules on a microfluidic chip" David A. Wicks and Paul C.H. Li , Anal. Chim. Acta, (accepted, in press).
  • An acoustic wave sensor incorporated with a microfluidic chip for analyzing muscle cell contraction, Paul C. H. Li, Weijie Wang and M. Parameswaran (Ash); Analyst  (2003)
  • Acoustic Wave Detection of Chemical Species Electrokinetically Transported Within a Capillary Tube; Paul C. H. Li and Ronald Prasad; Analyst (2003) 

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